Latest Clinical Pathology News

With the Americas failing to control coronavirus, many hospitals are at or close to capacity, PAHO director says mitchelc 19 Jan 2021... Read more
Published on: 2021-01-19
Source: PAHO
By: mitchelc
Anna Rana... Read more
Published on: 2021-01-19
Source: JOURNAL OF CLINICAL RESEARCH & BIOETHICS - table of contents
The COVID-19 pandemic has challenged our diagnostic services at a time when many histopathology departments already faced a diminishing workforce and increasing workload. Digital pathology (DP) has been hailed as a potential solution to at least some of the challenges faced. We present a survey of pathologists within a UK... Read more
Published on: 2021-01-19
Source: JOURNAL OF CLINICAL PATHOLOGY - short report
By: Browning, L., Fryer, E., Roskell, D., White, K., Colling, R., Rittscher, J., Verrill, C.
DICER1 is a highly conserved RNaseIII endoribonuclease that has a critical role in the biogenesis of microRNAs (miRNAs). miRNAs are small regulatory RNAs responsible for post-transcriptional gene silencing, controlling more than half of human protein-coding genes. This is achieved through the targeting and regulation of complementary RNA transcripts and has... Read more
Published on: 2021-01-19
Source: JOURNAL OF CLINICAL PATHOLOGY - recent issues
By: Thunders, M., Delahunt, B.
Background Coronavirus disease-2019 (COVID-19) has caused a great global threat to public health. The World Health Organization (WHO) has declared COVID-19 disease as a pandemic, affecting the human respiratory and other body systems, which urgently demands for better understanding of COVID-19 histopathogenesis. Objective Data on pathological changes in different organs... Read more
Published on: 2021-01-19
Source: JOURNAL OF CLINICAL PATHOLOGY - review
By: Deshmukh, V., Motwani, R., Kumar, A., Kumari, C., Raza, K.
Clinical question A 72-year-old man who was treated with a combination of simeprevir with peginterferon and ribavirin for hepatitis C virus (HCV) infection (genotype 1b) 5 years ago and has been treated as sustained virological response, was found to have a 2.6 cm tumourous lesion in the medial segment of... Read more
Published on: 2021-01-19
Source: JOURNAL OF CLINICAL PATHOLOGY - recent issues
By: Shimagaki, T., Maeda, T., Kinjo, N., Imai, D., Wang, H., Ohama, N., Edahiro, K., Edagawa, M., Takenaka, T., Ohmine, T., Yamaguchi, S., Konishi, K., Tsutsui, S., Matsuda, H.
It is estimated that food allergy affects 5% of adult population.1 We reported that food-induced anaphylaxis accounts for 21% of all anaphylaxis in British adults in a community setting.2 Food allergens are important confounders in the diagnostic evaluation of spontaneous anaphylaxis and chronic spontaneous urticaria (CSU) in adults. Best practice... Read more
Published on: 2021-01-19
Source: JOURNAL OF CLINICAL PATHOLOGY - postscript
By: Sooriyakumar, K., Mohamed, O., Osborne, T., Beck, S. C., Melchior, C., Heslegrave, J., Mathew, S., Baretto, R. L., Ekbote, A., Huissoon, A. P., Thirumala Krishna, M.
It is estimated that food allergy affects 5% of adult population.1 We reported that food-induced anaphylaxis accounts for 21% of all anaphylaxis in British adults in a community setting.2 Food allergens are important confounders in the diagnostic evaluation of spontaneous anaphylaxis and chronic spontaneous urticaria (CSU) in adults. Best practice... Read more
Published on: 2021-01-19
Source: JOURNAL OF CLINICAL PATHOLOGY - current issue only
By: Sooriyakumar, K., Mohamed, O., Osborne, T., Beck, S. C., Melchior, C., Heslegrave, J., Mathew, S., Baretto, R. L., Ekbote, A., Huissoon, A. P., Thirumala Krishna, M.
Aims The detection of programmed death-ligand 1 (PD-L1) protein expression on tumour cells by immunohistochemistry (IHC) is a predictor of response to immune checkpoint inhibitors. New immunotherapeutic options are changing the treatment paradigm for patients with advanced non-small cell lung cancer (NSCLC). The aim of this retrospective study was to... Read more
Published on: 2021-01-19
Source: JOURNAL OF CLINICAL PATHOLOGY - current issue only
By: Holmes, M., Mahar, A., Lum, T., Kao, S., Cooper, W. A.
It is estimated that food allergy affects 5% of adult population.1 We reported that food-induced anaphylaxis accounts for 21% of all anaphylaxis in British adults in a community setting.2 Food allergens are important confounders in the diagnostic evaluation of spontaneous anaphylaxis and chronic spontaneous urticaria (CSU) in adults. Best practice... Read more
Published on: 2021-01-19
Source: JOURNAL OF CLINICAL PATHOLOGY - recent issues
By: Sooriyakumar, K., Mohamed, O., Osborne, T., Beck, S. C., Melchior, C., Heslegrave, J., Mathew, S., Baretto, R. L., Ekbote, A., Huissoon, A. P., Thirumala Krishna, M.
The COVID-19 pandemic has challenged our diagnostic services at a time when many histopathology departments already faced a diminishing workforce and increasing workload. Digital pathology (DP) has been hailed as a potential solution to at least some of the challenges faced. We present a survey of pathologists within a UK... Read more
Published on: 2021-01-19
Source: JOURNAL OF CLINICAL PATHOLOGY - current issue only
By: Browning, L., Fryer, E., Roskell, D., White, K., Colling, R., Rittscher, J., Verrill, C.
Aims The detection of programmed death-ligand 1 (PD-L1) protein expression on tumour cells by immunohistochemistry (IHC) is a predictor of response to immune checkpoint inhibitors. New immunotherapeutic options are changing the treatment paradigm for patients with advanced non-small cell lung cancer (NSCLC). The aim of this retrospective study was to... Read more
Published on: 2021-01-19
Source: JOURNAL OF CLINICAL PATHOLOGY - recent issues
By: Holmes, M., Mahar, A., Lum, T., Kao, S., Cooper, W. A.

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