Citations - van der Velden Jacobus

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Published on: 2020-09-15
Source: van der Velden Jacobus
By: Ester P Olthof
No abstract... Read more
Published on: 2020-09-15
Source: van der Velden Jacobus
By: Ester P Olthof
No abstract... Read more
Published on: 2020-09-15
Source: van der Velden Jacobus
By: Ester P Olthof
No abstract... Read more
Published on: 2020-09-15
Source: van der Velden Jacobus
By: Ester P Olthof
No abstract... Read more
Published on: 2020-09-15
Source: van der Velden Jacobus
By: Ester P Olthof
No abstract... Read more
Published on: 2020-09-15
Source: van der Velden Jacobus
By: Ester P Olthof
Background - Variants within the alpha-tropomyosin gene (TPM1) cause dominantly inherited cardiomyopathies, including dilated (DCM), hypertrophic (HCM) and restrictive (RCM) cardiomyopathy. Here we investigated whether TPM1 variants observed in DCM and HCM patients affect cardiomyocyte physiology differently. Methods - We identified a large family with DCM carrying a recently identified... Read more
Published on: 2020-09-04
Source: van der Velden Jacobus
By: Larissa M Dorsch
CONCLUSION: Our data indicate that HMW-AGEs induce structural and functional cellular remodeling via a different working mechanism as the well-known LMW-AGEs. Results of our research open the door for new strategies targeting HMW-AGEs to improve cardiac outcome.... Read more
Published on: 2020-08-29
Source: van der Velden Jacobus
By: Dorien Deluyker
The chambers of the heart fulfill different hemodynamic functions, which are reflected in their structural and contractile properties. While the atria are highly elastic to allow filling from the venous system, the ventricles need to be able to produce sufficiently high pressures to eject blood into the circulation. The right... Read more
Published on: 2020-08-28
Source: van der Velden Jacobus
By: Edgar E Nollet
CONCLUSIONS: This study shows that the QTc interval in girls and women with TS is not prolonged compared to the general population derived from the literature, using both Bazett's and Hodges' formulas. Furthermore, girls show shorter QTc intervals compared to women, and a monosomy 45,X karyotype is not associated with... Read more
Published on: 2020-08-25
Source: van der Velden Jacobus
By: Iris D Noordman
In 2011 the Netherlands Heart Foundation allocated funding (CVON, Cardiovasculair Onderzoek Nederland) to stimulate collaboration between clinical and preclinical researchers on specific areas of research. One of those areas involves genetic heart diseases, which are frequently caused by pathogenic variants in genes that encode sarcomere proteins. In 2014, the DOSIS... Read more
Published on: 2020-08-12
Source: van der Velden Jacobus
By: R A de Boer
The prevalence of diabetic metabolic derangement (DMetD) has increased dramatically over the last decades. Although there is increasing evidence that DMetD is associated with cardiac dysfunction, the early DMetD-induced myocardial alterations remain incompletely understood. Here, we studied early DMetD-related cardiac changes in a clinically relevant large animal model. DMetD was... Read more
Published on: 2020-08-09
Source: van der Velden Jacobus
By: Ilkka Heinonen
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